Difference between revisions of "Airlie J. McCoy"

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[[File:Coffee.png|right|frame|link=]]
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<div style="margin-left: 25px; float: right;">__TOC__</div>
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==Protein Crystallography with Coffee==
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==Publications==
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Notes for protein crystallography students, written for the MRC-LMB Crystallography Course 2009
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 +
 
 +
===2017===
 +
 
 +
;Structure and evolution of ENTH and VHS/ENTH-like domains in tepsin.
 +
:Archuleta TL, Frazier MN, Monken AE, Kendall AK, Harp J, <span style="color:darkmagenta">McCoy AJ</span>, Creanza N, Jackson LP.
 +
:Traffic. 2017 Sep;18(9):590-603. [http://dx.doi.org/10.1111/tra.12499'''link''']
 +
 
 +
;Acknowledging Errors: Advanced Molecular Replacement with Phaser.
 +
:<span style="color:darkmagenta">McCoy AJ</span>
 +
:Methods Mol Biol. 2017;1607:421-453. [http://dx.doi.org/10.1007/978-1-4939-7000-1_18 '''link'''] Review.
 +
 
 +
;Ab initio solution of macromolecular crystal structures without direct methods.
 +
:<span style="color:darkmagenta">McCoy AJ</span>, Oeffner RD, Wrobel AG, Ojala JR, Tryggvason K, Lohkamp B, Read RJ.
 +
:Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3637-3641. [http://dx.doi.org/10.1073/pnas.1701640114 '''link'''] Epub 2017 Mar 21.
 +
 
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===2016===
 +
 
 +
;Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
 +
:Ma L, Umasankar PK, Wrobel AG, Lymar A, <span style="color:darkmagenta">McCoy AJ</span>, Holkar SS, Jha A, Pradhan-Sundd T, Watkins SC, Owen DJ, Traub LM.
 +
:Dev Cell. 2016 May 24. pii: S1534-5807(16)30280-5. [http://dx.doi.org/10.1016/j.devcel.2016.05.003 '''link''']
 +
 
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===2015===
 +
;A log-likelihood-gain intensity target for crystallographic phasing that accounts for experimental error.
 +
:Read RJ, <span style="color:darkmagenta">McCoy AJ</span>.
 +
:Acta Crystallogr D Struct Biol. 2016 Mar 1;72(Pt 3):375-87. [http://dx.doi.org/10.1107/S2059798315013236 '''link''']. Epub 2016 Mar 1.
 +
 
 +
;Advances in experimental phasing.
 +
:<span style="color:darkmagenta">McCoy AJ</span>, Schneider T.
 +
:Acta Crystallogr D Struct Biol. 2016 Mar 1;72(Pt 3):291-2. [http://dx.doi.org/10.1107/S2059798316003375 '''link''']. Epub 2016
 +
 
 +
;X-ray structure determination using low-resolution electron microscopy maps for molecular replacement.
 +
:Jackson RN, <span style="color:darkmagenta">McCoy AJ</span>, Terwilliger TC, Read RJ, Wiedenheft B.
 +
:Nat Protoc. 2015 Sep;10(9):1275-84. [http://dx.doi.org/10.1038/nprot.2015.069 '''link''']. Epub 2015 Jul 30.
 +
 
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;ANS complex of St John's wort PR-10 protein with 28 copies in the asymmetric unit: a fiendish combination of pseudosymmetry with tetartohedral twinning.
 +
:Sliwiak J, Dauter Z, Kowiel M, <span style="color:darkmagenta">McCoy AJ</span>, Read RJ, Jaskolski M.
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:Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):829-43. [http://dx.doi.org/10.1107/S1399004715001388 '''link'''] . Epub 2015 Mar 26.
 +
 
 +
===2014===
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 +
;Macromolecular X-ray structure determination using weak, single-wavelength anomalous data.
 +
:Bunkóczi G, <span style="color:darkmagenta">McCoy AJ</span>, Echols N, Grosse-Kunstleve RW, Adams PD, Holton JM, Read RJ, Terwilliger TC.
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:Nat Methods. 2015 Feb;12(2):127-30. [http://dx.doi.org/10.1038/nmeth.3212 '''link''']. Epub 2014 Dec 22.
 +
 
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;VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface.
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:Hesketh GG, Pérez-Dorado I, Jackson LP, Wartosch L, Schäfer IB, Gray SR, <span style="color:darkmagenta">McCoy AJ</span>, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MN, Luzio JP, Owen DJ.
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:Dev Cell. 2014 Jun 9;29(5):591-606.  Epub 2014 May 22.
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:[http://dx.doi.org/10.1016/j.devcel.2014.04.010 '''Dev Cell link''']
 +
 
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;Automated identification of elemental ions in macromolecular crystal structures.
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:Echols N, Morshed N, Afonine PV, <span style="color:darkmagenta">McCoy AJ</span>, Miller MD, Read RJ, Richardson JS, Terwilliger TC, Adams PD.
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:Acta Crystallogr D Biol Crystallogr. 2014 Apr;70(Pt 4):1104-14. Epub 2014 Mar 20.
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:[http://dx.doi.org/10.1107/S1399004714001308 '''IUCr link''']
 +
 
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;Likelihood-based molecular-replacement solution for a highly pathological crystal with tetartohedral twinning and sevenfold translational noncrystallographic symmetry.
 +
:Sliwiak 1, Jaskolski M, Dauter Z, <span style="color:darkmagenta">McCoy AJ</span>, Read RJ.
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:Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):471-80. Epub 2014 Jan 29.
 +
:[http://dx.doi.org/10.1107/S1399004713030319 '''IUCr link''']
 +
 
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;Automating crystallographic structure solution and refinement of protein-ligand complexes.
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:Echols N, Moriarty NW, Klei HE, Afonine PV, Bunkóczi G, Headd JJ, <span style="color:darkmagenta">McCoy AJ</span>, Oeffner RD, Read RJ, Terwilliger TC, Adams PD.
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:Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):144-54 Epub 2013 Dec 25.
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:[http://dx.doi.org/10.1107/S139900471302748X '''IUCr link''']
 +
 
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;Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism.
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:Ruprecht JJ, Hellawell AM, Harding M, Crichton PG, <span style="color:darkmagenta">McCoy AJ</span>, Kunji ER.
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:Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):E426-34 Epub 2014 Jan 13.
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:[http://dx.doi.org/10.1073/pnas.1320692111 '''PNAS link''']
 +
 
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===2013===
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;Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation.
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:Lewis M, Arnot CJ, Beeston H, <span style="color:darkmagenta">McCoy A</span>., Ashcroft AE, Gay NJ, Gangloff M.
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:Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20461-6. Epub 2013 Nov 26.
 +
:[http://dx.doi.org/10.1073/pnas.1317002110 '''download pdf''']
 +
 
 +
;Phaser.MRage<nowiki>:</nowiki> automated molecular replacement.
 +
:Bunkóczi G, Echols N, <span style="color:darkmagenta">McCoy AJ</span>, Oeffner RD, Adams PD, Read RJ.
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:Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2276-86. Epub 2013 Oct 18.
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:[http://dx.doi.org/10.1107/S0907444913022750 '''IUCr link''']
  
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* [http://www-structmed.cimr.cam.ac.uk/Personal/airlie/protein_crystallography_with_coffee_2009d_small.pdf Protein Crystallography with Coffee] (''Low Resolution Graphics'' 2.7MB)
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;SCEDS<nowiki>:</nowiki> protein fragments for molecular replacement in Phaser.
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*[http://www-structmed.cimr.cam.ac.uk/Personal/airlie/protein_crystallography_with_coffee_2009d_large.pdf Protein Crystallography with Coffee] (''High Resolution Graphics'' 8.1MB)
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:<span style="color:darkmagenta">McCoy AJ</span>, Nicholls RA, Schneider TR.
 +
:Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2216-25. [http://dx.doi.org/10.1107/S0907444913021811 '''doi''']. Epub 2013 Oct 4.
 +
:[http://scripts.iucr.org/cgi-bin/paper?ba5209 '''IUCr link''']
  
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These notes give an introduction to protein crystallography. The title "Protein Crystallography with Coffee" comes about because each section is designed to be read while drinking a cup of coffee (or tea!). At about 6000 words, it should take the average scientific reader 20 minutes to finish "sipping" a section. With five sections, it should only take a week of coffee breaks to finish reading.
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;Improved estimates of coordinate error for molecular replacement.
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:Oeffner RD, Bunkóczi G, <span style="color:darkmagenta">McCoy AJ</span>, Read RJ.
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:Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2209-15. [http://dx.doi.org/10.1107/S0907444913023512 '''doi''']. Epub 2013 Oct 12.
 +
:[http://scripts.iucr.org/cgi-bin/paper?ba5212 '''IUCr link''']
  
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This could be considered a postmodern approach to crystallography. It mixes the science with history and anecdotes to describe not only the "what and why" but also the "who and when".  
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;Intensity statistics in the presence of translational noncrystallographic symmetry.
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:Read RJ, Adams PD, <span style="color:darkmagenta">McCoy AJ</span>.
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:Acta Crystallogr D Biol Crystallogr 2013 Feb;69(Pt 2):176-83. Epub  Jan 16.
 +
:[http://scripts.iucr.org/cgi-bin/paper?dz5268 '''IUCr link''']
  
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''Enjoy!''
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===2012===
 +
;Graphical tools for macromolecular crystallography in PHENIX.
 +
:Echols N, Grosse-Kunstleve RW, Afonine PV, Bunkóczi G, Chen VB, Headd JJ, <span style="color:darkmagenta">McCoy AJ</span>, Moriarty NW, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Adams PD.
 +
:J Appl Crystallogr. 2012 Jun 1;45(Pt 3):581-586. Epub 2012 May 16.
 +
:[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359726/pdf/j-45-00581.pdf '''download pdf''']
  
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==Publications==
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===2011===
 +
;The Phenix software for automated determination of macromolecular structures.
 +
:Adams PD, Afonine PV, Bunkóczi G, Chen VB, Echols N, Headd JJ, Hung LW, Jain S, Kapral GJ, Grosse Kunstleve RW, McCoy AJ, Moriarty NW, Oeffner RD, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Zwart PH.
 +
:Methods. 2011 Sep;55(1):94-106. doi: 10.1016/j.ymeth.2011.07.005. Epub 2011 Jul 29.
 +
:[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193589/pdf/nihms319608.pdf '''download pdf''']
 +
 
 +
;Overview of the CCP4 suite and current developments
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:Winn MD, Ballard CC, Cowtan KD, Dodson EJ, Emsley P, Evans PR, Keegan RM, Krissinel EB, Leslie AG, <span style="color:darkmagenta">McCoy A</span>, McNicholas SJ, Murshudov GN, Pannu NS, Potterton EA, Powell HR, Read RJ, Vagin A, Wilson KS.
 +
:Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):235-242
 +
:[http://scripts.iucr.org/cgi-bin/paper?dz5219 '''Acta Cryst D''']
 +
 
 +
;Using SAD data in Phaser
 +
:Read RJ, <span style="color:darkmagenta">McCoy AJ</span>
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:Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):338-344
 +
:[http://scripts.iucr.org/cgi-bin/paper?ba5159 '''Acta Cryst D''']
 +
 
 +
===2010===
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;A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex.
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:Jackson LP, Kelly BT, <span style="color:darkmagenta">McCoy AJ</span>, Gaffry T, James LC, Collins BM, Höning S, Evans PR, Owen DJ.
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:Cell. 2010 Jun 25;141(7):1220-9.
 +
:[http://www.cell.com/abstract/S0092-8674(10)00542-8 '''Cell'''] (subscription required)
 +
 
 +
;Experimental phasing<nowiki>:</nowiki>  best practice and pitfalls.
 +
:<span style="color:darkmagenta">McCoy AJ</span>, Read RJ.
 +
:Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):458-69. Epub 2010 Mar 24.
 +
:[http://scripts.iucr.org/cgi-bin/paper?ba5142 '''Acta Cryst D''']
 +
 
 +
;PHENIX<nowiki>:</nowiki> a comprehensive Python-based system for macromolecular structure solution.
 +
:Adams PD, Afonine PV, Bunkóczi G, Chen VB, Davis IW, Echols N, Headd JJ, Hung LW, Kapral GJ, Grosse-Kunstleve RW, <span style="color:darkmagenta">McCoy AJ</span>, Moriarty NW, Oeffner R, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Zwart PH.
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:Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):213-21. Epub 2010 Jan 22.
 +
:[http://scripts.iucr.org/cgi-bin/paper?dz5186 '''Acta Cryst D''']
 +
 
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===2009===
 
;Decision-making in structure solution using Bayesian estimates of map quality<nowiki>:</nowiki> the PHENIX AutoSol wizard  
 
;Decision-making in structure solution using Bayesian estimates of map quality<nowiki>:</nowiki> the PHENIX AutoSol wizard  
 
:Terwilliger TC, Adams PD, Read RJ, <span style="color:darkmagenta">McCoy AJ</span> , Moriarty NW, Grosse-Kunstleve RW, Afonine PV, Zwart PH, Hung LW.
 
:Terwilliger TC, Adams PD, Read RJ, <span style="color:darkmagenta">McCoy AJ</span> , Moriarty NW, Grosse-Kunstleve RW, Afonine PV, Zwart PH, Hung LW.
 
:Acta Crystallogr D Biol Crystallogr. 2009 Jun;65(Pt 6):582-601
 
:Acta Crystallogr D Biol Crystallogr. 2009 Jun;65(Pt 6):582-601
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:[http://www.phaser.cimr.cam.ac.uk/images/b/b2/He5368.pdf '''download pdf''']
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:[http://scripts.iucr.org/cgi-bin/paper?ea5095 '''Acta Cryst''']
  
 +
===2008===
 
;A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
 
;A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
 
:Kelly BT, <span style="color:darkmagenta">McCoy AJ</span>, Späte K, Miller SE, Evans PR, Höning S, Owen DJ.
 
:Kelly BT, <span style="color:darkmagenta">McCoy AJ</span>, Späte K, Miller SE, Evans PR, Höning S, Owen DJ.
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:Evans P, <span style="color:darkmagenta">McCoy A</span>.
 
:Evans P, <span style="color:darkmagenta">McCoy A</span>.
 
:Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):1-10. Epub 2007 Dec 5.
 
:Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):1-10. Epub 2007 Dec 5.
−
:[http://www.phaser.cimr.cam.ac.uk/images/8/86/Ba5108.pdf '''download pdf''']
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:[http://scripts.iucr.org/cgi-bin/paper?ba5108 '''Acta Cryst D''']
  
 
;Automated structure solution with the PHENIX suite
 
;Automated structure solution with the PHENIX suite
 
:Zwart PH, Afonine PV, Grosse-Kunstleve RW, Hung LW, Ioerger TR, <span style="color:darkmagenta">McCoy AJ</span>, McKee E, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Storoni LC, Terwilliger TC, Adams PD.
 
:Zwart PH, Afonine PV, Grosse-Kunstleve RW, Hung LW, Ioerger TR, <span style="color:darkmagenta">McCoy AJ</span>, McKee E, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Storoni LC, Terwilliger TC, Adams PD.
 
:Methods Mol Biol. 2008;426:419-35.
 
:Methods Mol Biol. 2008;426:419-35.
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:[http://www.phaser.cimr.cam.ac.uk/images/8/8d/Zwart_etal_2008_preview.pdf '''preview pdf'''] [http://dx.doi.org/10.1007/978-1-60327-058-8 '''doi'''] Digital Object Identifier
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:[http://dx.doi.org/10.1007/978-1-60327-058-8 '''doi'''] Digital Object Identifier
  
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===2007===
 
;A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles  
 
;A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles  
 
:Miller SE, Collins BM, <span style="color:darkmagenta">McCoy AJ</span>, Robinson MS, Owen DJ.
 
:Miller SE, Collins BM, <span style="color:darkmagenta">McCoy AJ</span>, Robinson MS, Owen DJ.
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:Nature. 2007 Nov 8;450(7167):259-64. Epub 2007 Oct 14.
 
:Nature. 2007 Nov 8;450(7167):259-64. Epub 2007 Oct 14.
 
:[http://www.nature.com/nature/journal/v450/n7167/abs/nature06249.html '''Nature'''] (subscription required)
 
:[http://www.nature.com/nature/journal/v450/n7167/abs/nature06249.html '''Nature'''] (subscription required)
 +
 +
;Solving structures of protein complexes by molecular replacement with Phaser
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:<span style="color:darkmagenta">McCoy AJ</span>
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:Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):32-41. Epub 2006 Dec 13.
 +
:[http://scripts.iucr.org/cgi-bin/paper?ba5095 '''Acta Cryst D''']
 +
 +
;Phaser crystallographic software
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:<span style="color:darkmagenta">McCoy AJ</span>, Grosse-Kunstleve RW, Adams PD, Winn MD, Storoni LC and Read RJ.
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:J. Appl. Cryst. (2007). 40, 658-674.
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:[http://scripts.iucr.org/cgi-bin/paper?he5368 '''J Appl Cryst''']
  
 
;β-Edge interactions in a pentadecameric human antibody Vκ domain.
 
;β-Edge interactions in a pentadecameric human antibody Vκ domain.
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:[http://dx.doi.org/10.1016/j.jmb.2006.10.093 '''doi'''] Digital Object Identifier
 
:[http://dx.doi.org/10.1016/j.jmb.2006.10.093 '''doi'''] Digital Object Identifier
  
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;Phaser crystallographic software
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===2006===
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:<span style="color:darkmagenta">McCoy AJ</span>, Grosse-Kunstleve RW, Adams PD, Winn MD, Storoni LC and Read RJ.
 
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:J. Appl. Cryst. (2007). 40, 658-674.
 
−
:[http://www.phaser.cimr.cam.ac.uk/images/b/b2/He5368.pdf '''download pdf''']
 
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;Solving structures of protein complexes by molecular replacement with Phaser
 
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:<span style="color:darkmagenta">McCoy AJ</span>
 
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:Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):32-41. Epub 2006 Dec 13.
 
−
:[http://www.phaser.cimr.cam.ac.uk/images/4/40/Ba5095.pdf '''download pdf''']
 
  
 
;Crystal structure of rab11 in complex with rab11 family interacting protein 2  
 
;Crystal structure of rab11 in complex with rab11 family interacting protein 2  
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:[http://www.structure.org/content/article/abstract?uid=PIIS0969212606002930 '''Structure'''] (subscription required)
 
:[http://www.structure.org/content/article/abstract?uid=PIIS0969212606002930 '''Structure'''] (subscription required)
  
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===2005===
 
;Likelihood-enhanced fast translation functions  
 
;Likelihood-enhanced fast translation functions  
 
:<span style="color:darkmagenta">McCoy AJ</span>, Grosse-Kunstleve RW, Storoni LC, Read RJ.
 
:<span style="color:darkmagenta">McCoy AJ</span>, Grosse-Kunstleve RW, Storoni LC, Read RJ.
 
:Acta Crystallogr D Biol Crystallogr. 2005 Apr;61(Pt 4):458-64. Epub 2005 Mar 24.
 
:Acta Crystallogr D Biol Crystallogr. 2005 Apr;61(Pt 4):458-64. Epub 2005 Mar 24.
−
:[http://www.phaser.cimr.cam.ac.uk/images/6/63/Gx5042.pdf '''download pdf''']  
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:[http://scripts.iucr.org/cgi-bin/paper?gx5042.pdf '''Acta Cryst D''']  
  
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===2004===
 
;Liking Likelihood  
 
;Liking Likelihood  
 
:<span style="color:darkmagenta">McCoy AJ</span>
 
:<span style="color:darkmagenta">McCoy AJ</span>
 
:Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2169-83. Epub 2004 Nov 26.
 
:Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2169-83. Epub 2004 Nov 26.
−
:[http://www.phaser.cimr.cam.ac.uk/images/4/46/Ba5064.pdf '''download pdf''']
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:[http://scripts.iucr.org/cgi-bin/paper?ba5064 '''Acta Cryst D''']
  
 
;Simple algorithm for a maximum-likelihood SAD function  
 
;Simple algorithm for a maximum-likelihood SAD function  
 
:<span style="color:darkmagenta">McCoy AJ</span>, Storoni LC, Read RJ.
 
:<span style="color:darkmagenta">McCoy AJ</span>, Storoni LC, Read RJ.
 
:Acta Crystallogr D Biol Crystallogr. 2004 Jul;60(Pt 7):1220-8. Epub 2004 Jun 22.
 
:Acta Crystallogr D Biol Crystallogr. 2004 Jul;60(Pt 7):1220-8. Epub 2004 Jun 22.
−
:[http://www.phaser.cimr.cam.ac.uk/images/c/c3/Ea5015.pdf '''download pdf''']
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:[http://scripts.iucr.org/cgi-bin/paper?ea5015 '''Acta Cryst D''']
  
 
;Likelihood-enhanced fast rotation functions  
 
;Likelihood-enhanced fast rotation functions  
 
:Storoni LC, <span style="color:darkmagenta">McCoy AJ</span>, Read RJ.
 
:Storoni LC, <span style="color:darkmagenta">McCoy AJ</span>, Read RJ.
 
:Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):432-8. Epub 2004 Feb 25.
 
:Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):432-8. Epub 2004 Feb 25.
−
:[http://www.phaser.cimr.cam.ac.uk/images/3/3a/Ad5007.pdf '''download pdf''']
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:[http://scripts.iucr.org/cgi-bin/paper?ad5007 '''Acta Cryst D'''] [http://www-structmed.cimr.cam.ac.uk/Personal/randy/pubs/ad5007.pdf '''pdf''']
  
 +
===2003===
 
;Recent developments in the PHENIX software for automated crystallographic structure determination
 
;Recent developments in the PHENIX software for automated crystallographic structure determination
 
:Adams PD, Gopal K, Grosse-Kunstleve RW, Hung LW, Ioerger TR, <span style="color:darkmagenta">McCoy AJ</span>, Moriarty NW, Pai RK, Read RJ, Romo TD, Sacchettini JC, Sauter NK, Storoni LC, Terwilliger TC.
 
:Adams PD, Gopal K, Grosse-Kunstleve RW, Hung LW, Ioerger TR, <span style="color:darkmagenta">McCoy AJ</span>, Moriarty NW, Pai RK, Read RJ, Romo TD, Sacchettini JC, Sauter NK, Storoni LC, Terwilliger TC.
 
:J Synchrotron Radiat. 2004 Jan 1;11(Pt 1):53-5. Epub 2003 Nov 28.
 
:J Synchrotron Radiat. 2004 Jan 1;11(Pt 1):53-5. Epub 2003 Nov 28.
−
:[http://www.phaser.cimr.cam.ac.uk/images/e/e/Ys0029.pdf '''download pdf''']
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:[http://scripts.iucr.org/cgi-bin/paper?ys0029.pdf '''J Synch Radia''']
  
 
;Application of the complex multivariate normal distribution to crystallographic methods with insights into multiple isomorphous replacement phasing
 
;Application of the complex multivariate normal distribution to crystallographic methods with insights into multiple isomorphous replacement phasing
 
:Pannu NS, <span style="color:darkmagenta">McCoy AJ</span>, Read RJ.
 
:Pannu NS, <span style="color:darkmagenta">McCoy AJ</span>, Read RJ.
 
:Acta Crystallogr D Biol Crystallogr. 2003 Oct;59(Pt 10):1801-8. Epub 2003 Sep 19.
 
:Acta Crystallogr D Biol Crystallogr. 2003 Oct;59(Pt 10):1801-8. Epub 2003 Sep 19.
−
:[http://www.phaser.cimr.cam.ac.uk/images/6/61/Wd5000.pdf '''download pdf''']
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:[http://scripts.iucr.org/cgi-bin/paper?wd5000.pdf '''Acta Cryst D''']
  
 
;Structure of β-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity
 
;Structure of β-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity
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:[http://dx.doi.org/10.1016/S0022-2836(02)01382-7 '''doi'''] Digital Object Identifier
 
:[http://dx.doi.org/10.1016/S0022-2836(02)01382-7 '''doi'''] Digital Object Identifier
  
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===2002===
 
;New applications of maximum likelihood and Bayesian statistics in macromolecular crystallography
 
;New applications of maximum likelihood and Bayesian statistics in macromolecular crystallography
 
:<span style="color:darkmagenta">McCoy AJ</span>
 
:<span style="color:darkmagenta">McCoy AJ</span>
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:Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, <span style="color:darkmagenta">McCoy AJ</span>, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC.
 
:Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, <span style="color:darkmagenta">McCoy AJ</span>, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC.
 
:Acta Crystallogr D Biol Crystallogr. 2002 Nov;58(Pt 11):1948-54. Epub 2002 Oct 21.
 
:Acta Crystallogr D Biol Crystallogr. 2002 Nov;58(Pt 11):1948-54. Epub 2002 Oct 21.
−
:[http://www.phaser.cimr.cam.ac.uk/images/d/dc/Ba5027.pdf '''download pdf''']
+
:[http://scripts.iucr.org/cgi-bin/paper?ba5027 '''Acta Cryst D''']
  
 
;Molecular architecture and functional model of the endocytic AP2 complex  
 
;Molecular architecture and functional model of the endocytic AP2 complex  
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:[http://www.structure.org/content/article/abstract?uid=PIIS0092867402007353 '''Cell'''] (subscription required)
 
:[http://www.structure.org/content/article/abstract?uid=PIIS0092867402007353 '''Cell'''] (subscription required)
  
 +
===2001===
 +
:No publications
 +
 +
===2000===
 
;ScFv multimers of the anti-neuraminidase antibody NC10<nowiki>:</nowiki> shortening of the linker in single-chain Fv fragment assembled in V(L) to V(H) orientation drives the formation of dimers, trimers, tetramers and higher molecular mass multimers  
 
;ScFv multimers of the anti-neuraminidase antibody NC10<nowiki>:</nowiki> shortening of the linker in single-chain Fv fragment assembled in V(L) to V(H) orientation drives the formation of dimers, trimers, tetramers and higher molecular mass multimers  
 
:Dolezal O, Pearce LA, Lawrence LJ, <span style="color:darkmagenta">McCoy AJ</span>, Hudson PJ, Kortt AA.
 
:Dolezal O, Pearce LA, Lawrence LJ, <span style="color:darkmagenta">McCoy AJ</span>, Hudson PJ, Kortt AA.
 
:Protein Eng. 2000 Aug;13(8):565-74.
 
:Protein Eng. 2000 Aug;13(8):565-74.
−
:[http://www.phaser.cimr.cam.ac.uk/images/1/19/Dolezal_etal_2000.pdf '''download pdf''']
+
:[http://dx.doi.org/10.1093/protein/13.8.565 '''doi'''] Digital Object Identifier
  
 
;The conformational activation of antithrombin. A 2.85-A structure of a fluorescein derivative reveals an electrostatic link between the hinge and heparin binding regions.  
 
;The conformational activation of antithrombin. A 2.85-A structure of a fluorescein derivative reveals an electrostatic link between the hinge and heparin binding regions.  
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:<nowiki>*</nowiki>authors contributed equally
 
:<nowiki>*</nowiki>authors contributed equally
 
:J Biol Chem. 2000 May 19;275(20):15377-83
 
:J Biol Chem. 2000 May 19;275(20):15377-83
−
:[http://www.phaser.cimr.cam.ac.uk/images/4/45/JBC-2000-Huntington-15377-83.pdf '''download pdf''']
+
:[http://dx.doi.org/10.1074/jbc.275.20.15377 '''doi'''] Digital Object Identifier
  
 +
===1999===
 
;Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod  
 
;Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod  
 
:<span style="color:darkmagenta">McCoy AJ</span>, Fucini P, Noegel AA, Stewart M.
 
:<span style="color:darkmagenta">McCoy AJ</span>, Fucini P, Noegel AA, Stewart M.
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:Atwell JL, Breheney KA, Lawrence LJ, <span style="color:darkmagenta">McCoy AJ</span>, Kortt AA, Hudson PJ.
 
:Atwell JL, Breheney KA, Lawrence LJ, <span style="color:darkmagenta">McCoy AJ</span>, Kortt AA, Hudson PJ.
 
:Protein Eng. 1999 Jul;12(7):597-604.
 
:Protein Eng. 1999 Jul;12(7):597-604.
−
:[http://www.phaser.cimr.cam.ac.uk/images/e/e3/Atwell_etal_1999.pdf '''download pdf''']
+
:[http://dx.doi.org/10.1093/protein/12.7.597 '''doi'''] Digital Object Identifier
  
 
;Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import
 
;Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import
Line 139: Line 275:
 
:[http://dx.doi.org/10.1006/jmbi.1999.2775 '''doi'''] Digital Object Identifier
 
:[http://dx.doi.org/10.1006/jmbi.1999.2775 '''doi'''] Digital Object Identifier
  
 +
===1998===
 
;The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2)
 
;The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2)
 
:Stewart M, Kent HM, <span style="color:darkmagenta">McCoy AJ</span>.
 
:Stewart M, Kent HM, <span style="color:darkmagenta">McCoy AJ</span>.
Line 160: Line 297:
 
:[http://www.nature.com/nsmb/journal/v5/n3/abs/nsb0398-184.html '''Nature Structural Biology'''] (subscription required)
 
:[http://www.nature.com/nsmb/journal/v5/n3/abs/nsb0398-184.html '''Nature Structural Biology'''] (subscription required)
  
 +
===1997===
 
;Crystallization and preliminary X-Ray diffraction characterization of a dimerizing fragment of the rod domain of the Dictyostelium gelation factor (ABP-120)
 
;Crystallization and preliminary X-Ray diffraction characterization of a dimerizing fragment of the rod domain of the Dictyostelium gelation factor (ABP-120)
 
:Fucini P, <span style="color:darkmagenta">McCoy AJ</span>, Gomez-Ortiz M, Schleicher M, Noegel AA, Stewart M.
 
:Fucini P, <span style="color:darkmagenta">McCoy AJ</span>, Gomez-Ortiz M, Schleicher M, Noegel AA, Stewart M.
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:Kortt AA, Lah M, Oddie GW, Gruen CL, Burns JE, Pearce LA, Atwell JL, <span style="color:darkmagenta">McCoy AJ</span>, Howlett GJ, Metzger DW, Webster RG, Hudson PJ.
 
:Kortt AA, Lah M, Oddie GW, Gruen CL, Burns JE, Pearce LA, Atwell JL, <span style="color:darkmagenta">McCoy AJ</span>, Howlett GJ, Metzger DW, Webster RG, Hudson PJ.
 
:Protein Eng. 1997 Apr;10(4):423-33.
 
:Protein Eng. 1997 Apr;10(4):423-33.
−
:[http://www.phaser.cimr.cam.ac.uk/images/f/f8/Kortt_etal_1997.pdf '''download pdf''']
+
:[http://dx.doi.org/10.1093/protein/10.4.423 '''doi'''] Digital Object Identifier
 +
 
 +
===1996===
 +
;Protein Structure and Interaction
 +
:<span style="color:darkmagenta">McCoy AJ</span>
 +
:Thesis (Ph. D)
 +
:[http://cat.lib.unimelb.edu.au/search~S30?/amccoy+aj/amccoy+aj/-3%2C0%2C0%2CB/frameset&FF=amccoy+airlie+janet&1%2C1%2C/indexsort=- '''University of Melbourne Library'''] (not available for loan)

Latest revision as of 09:48, 9 March 2018

Publications

2017

Structure and evolution of ENTH and VHS/ENTH-like domains in tepsin.
Archuleta TL, Frazier MN, Monken AE, Kendall AK, Harp J, McCoy AJ, Creanza N, Jackson LP.
Traffic. 2017 Sep;18(9):590-603. link
Acknowledging Errors
Advanced Molecular Replacement with Phaser.
McCoy AJ
Methods Mol Biol. 2017;1607:421-453. link Review.
Ab initio solution of macromolecular crystal structures without direct methods.
McCoy AJ, Oeffner RD, Wrobel AG, Ojala JR, Tryggvason K, Lohkamp B, Read RJ.
Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3637-3641. link Epub 2017 Mar 21.

2016

Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Ma L, Umasankar PK, Wrobel AG, Lymar A, McCoy AJ, Holkar SS, Jha A, Pradhan-Sundd T, Watkins SC, Owen DJ, Traub LM.
Dev Cell. 2016 May 24. pii: S1534-5807(16)30280-5. link

2015

A log-likelihood-gain intensity target for crystallographic phasing that accounts for experimental error.
Read RJ, McCoy AJ.
Acta Crystallogr D Struct Biol. 2016 Mar 1;72(Pt 3):375-87. link. Epub 2016 Mar 1.
Advances in experimental phasing.
McCoy AJ, Schneider T.
Acta Crystallogr D Struct Biol. 2016 Mar 1;72(Pt 3):291-2. link. Epub 2016
X-ray structure determination using low-resolution electron microscopy maps for molecular replacement.
Jackson RN, McCoy AJ, Terwilliger TC, Read RJ, Wiedenheft B.
Nat Protoc. 2015 Sep;10(9):1275-84. link. Epub 2015 Jul 30.
ANS complex of St John's wort PR-10 protein with 28 copies in the asymmetric unit
a fiendish combination of pseudosymmetry with tetartohedral twinning.
Sliwiak J, Dauter Z, Kowiel M, McCoy AJ, Read RJ, Jaskolski M.
Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):829-43. link . Epub 2015 Mar 26.

2014

Macromolecular X-ray structure determination using weak, single-wavelength anomalous data.
Bunkóczi G, McCoy AJ, Echols N, Grosse-Kunstleve RW, Adams PD, Holton JM, Read RJ, Terwilliger TC.
Nat Methods. 2015 Feb;12(2):127-30. link. Epub 2014 Dec 22.
VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface.
Hesketh GG, Pérez-Dorado I, Jackson LP, Wartosch L, Schäfer IB, Gray SR, McCoy AJ, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MN, Luzio JP, Owen DJ.
Dev Cell. 2014 Jun 9;29(5):591-606. Epub 2014 May 22.
Dev Cell link
Automated identification of elemental ions in macromolecular crystal structures.
Echols N, Morshed N, Afonine PV, McCoy AJ, Miller MD, Read RJ, Richardson JS, Terwilliger TC, Adams PD.
Acta Crystallogr D Biol Crystallogr. 2014 Apr;70(Pt 4):1104-14. Epub 2014 Mar 20.
IUCr link
Likelihood-based molecular-replacement solution for a highly pathological crystal with tetartohedral twinning and sevenfold translational noncrystallographic symmetry.
Sliwiak 1, Jaskolski M, Dauter Z, McCoy AJ, Read RJ.
Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):471-80. Epub 2014 Jan 29.
IUCr link
Automating crystallographic structure solution and refinement of protein-ligand complexes.
Echols N, Moriarty NW, Klei HE, Afonine PV, Bunkóczi G, Headd JJ, McCoy AJ, Oeffner RD, Read RJ, Terwilliger TC, Adams PD.
Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):144-54 Epub 2013 Dec 25.
IUCr link
Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism.
Ruprecht JJ, Hellawell AM, Harding M, Crichton PG, McCoy AJ, Kunji ER.
Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):E426-34 Epub 2014 Jan 13.
PNAS link

2013

Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation.
Lewis M, Arnot CJ, Beeston H, McCoy A., Ashcroft AE, Gay NJ, Gangloff M.
Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20461-6. Epub 2013 Nov 26.
download pdf
Phaser.MRage: automated molecular replacement.
Bunkóczi G, Echols N, McCoy AJ, Oeffner RD, Adams PD, Read RJ.
Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2276-86. Epub 2013 Oct 18.
IUCr link
SCEDS: protein fragments for molecular replacement in Phaser.
McCoy AJ, Nicholls RA, Schneider TR.
Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2216-25. doi. Epub 2013 Oct 4.
IUCr link
Improved estimates of coordinate error for molecular replacement.
Oeffner RD, Bunkóczi G, McCoy AJ, Read RJ.
Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2209-15. doi. Epub 2013 Oct 12.
IUCr link
Intensity statistics in the presence of translational noncrystallographic symmetry.
Read RJ, Adams PD, McCoy AJ.
Acta Crystallogr D Biol Crystallogr 2013 Feb;69(Pt 2):176-83. Epub Jan 16.
IUCr link

2012

Graphical tools for macromolecular crystallography in PHENIX.
Echols N, Grosse-Kunstleve RW, Afonine PV, Bunkóczi G, Chen VB, Headd JJ, McCoy AJ, Moriarty NW, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Adams PD.
J Appl Crystallogr. 2012 Jun 1;45(Pt 3):581-586. Epub 2012 May 16.
download pdf

2011

The Phenix software for automated determination of macromolecular structures.
Adams PD, Afonine PV, Bunkóczi G, Chen VB, Echols N, Headd JJ, Hung LW, Jain S, Kapral GJ, Grosse Kunstleve RW, McCoy AJ, Moriarty NW, Oeffner RD, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Zwart PH.
Methods. 2011 Sep;55(1):94-106. doi: 10.1016/j.ymeth.2011.07.005. Epub 2011 Jul 29.
download pdf
Overview of the CCP4 suite and current developments
Winn MD, Ballard CC, Cowtan KD, Dodson EJ, Emsley P, Evans PR, Keegan RM, Krissinel EB, Leslie AG, McCoy A, McNicholas SJ, Murshudov GN, Pannu NS, Potterton EA, Powell HR, Read RJ, Vagin A, Wilson KS.
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):235-242
Acta Cryst D
Using SAD data in Phaser
Read RJ, McCoy AJ
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):338-344
Acta Cryst D

2010

A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex.
Jackson LP, Kelly BT, McCoy AJ, Gaffry T, James LC, Collins BM, Höning S, Evans PR, Owen DJ.
Cell. 2010 Jun 25;141(7):1220-9.
Cell (subscription required)
Experimental phasing: best practice and pitfalls.
McCoy AJ, Read RJ.
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):458-69. Epub 2010 Mar 24.
Acta Cryst D
PHENIX: a comprehensive Python-based system for macromolecular structure solution.
Adams PD, Afonine PV, Bunkóczi G, Chen VB, Davis IW, Echols N, Headd JJ, Hung LW, Kapral GJ, Grosse-Kunstleve RW, McCoy AJ, Moriarty NW, Oeffner R, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Zwart PH.
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):213-21. Epub 2010 Jan 22.
Acta Cryst D

2009

Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard
Terwilliger TC, Adams PD, Read RJ, McCoy AJ , Moriarty NW, Grosse-Kunstleve RW, Afonine PV, Zwart PH, Hung LW.
Acta Crystallogr D Biol Crystallogr. 2009 Jun;65(Pt 6):582-601
Acta Cryst

2008

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
Kelly BT, McCoy AJ, Späte K, Miller SE, Evans PR, Höning S, Owen DJ.
Nature. 2008 Dec 18;456(7224):976-79
Nature (subscription required)
An introduction to molecular replacement
Evans P, McCoy A.
Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):1-10. Epub 2007 Dec 5.
Acta Cryst D
Automated structure solution with the PHENIX suite
Zwart PH, Afonine PV, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ, McKee E, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Storoni LC, Terwilliger TC, Adams PD.
Methods Mol Biol. 2008;426:419-35.
doi Digital Object Identifier

2007

A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles
Miller SE, Collins BM, McCoy AJ, Robinson MS, Owen DJ.
Nature. 2007 Nov 22;450(7169):570-4
Nature (subscription required)
High-resolution structure prediction and the crystallographic phase problem
Qian B, Raman S, Das R, Bradley P, McCoy AJ, Read RJ, Baker D.
Nature. 2007 Nov 8;450(7167):259-64. Epub 2007 Oct 14.
Nature (subscription required)
Solving structures of protein complexes by molecular replacement with Phaser
McCoy AJ
Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):32-41. Epub 2006 Dec 13.
Acta Cryst D
Phaser crystallographic software
McCoy AJ, Grosse-Kunstleve RW, Adams PD, Winn MD, Storoni LC and Read RJ.
J. Appl. Cryst. (2007). 40, 658-674.
J Appl Cryst
β-Edge interactions in a pentadecameric human antibody Vκ domain.
James LC, Jones PC, McCoy A, Tennent GA, Pepys MB, Famm K, Winter G.
J Mol Biol. 2007 Mar 30;367(3):603-8. Epub 2006 Nov 3.
doi Digital Object Identifier

2006

Crystal structure of rab11 in complex with rab11 family interacting protein 2
Jagoe WN, Lindsay AJ, Read RJ, McCoy AJ, McCaffrey MW, Khan AR.
Structure. 2006 Aug;14(8):1273-83.
Structure (subscription required)

2005

Likelihood-enhanced fast translation functions
McCoy AJ, Grosse-Kunstleve RW, Storoni LC, Read RJ.
Acta Crystallogr D Biol Crystallogr. 2005 Apr;61(Pt 4):458-64. Epub 2005 Mar 24.
Acta Cryst D

2004

Liking Likelihood
McCoy AJ
Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2169-83. Epub 2004 Nov 26.
Acta Cryst D
Simple algorithm for a maximum-likelihood SAD function
McCoy AJ, Storoni LC, Read RJ.
Acta Crystallogr D Biol Crystallogr. 2004 Jul;60(Pt 7):1220-8. Epub 2004 Jun 22.
Acta Cryst D
Likelihood-enhanced fast rotation functions
Storoni LC, McCoy AJ, Read RJ.
Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):432-8. Epub 2004 Feb 25.
Acta Cryst D pdf

2003

Recent developments in the PHENIX software for automated crystallographic structure determination
Adams PD, Gopal K, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ, Moriarty NW, Pai RK, Read RJ, Romo TD, Sacchettini JC, Sauter NK, Storoni LC, Terwilliger TC.
J Synchrotron Radiat. 2004 Jan 1;11(Pt 1):53-5. Epub 2003 Nov 28.
J Synch Radia
Application of the complex multivariate normal distribution to crystallographic methods with insights into multiple isomorphous replacement phasing
Pannu NS, McCoy AJ, Read RJ.
Acta Crystallogr D Biol Crystallogr. 2003 Oct;59(Pt 10):1801-8. Epub 2003 Sep 19.
Acta Cryst D
Structure of β-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity
McCoy AJ, Pei XY, Skinner R, Abrahams JP, Carrell RW.
J Mol Biol. 2003 Feb 21;326(3):823-33.
doi Digital Object Identifier

2002

New applications of maximum likelihood and Bayesian statistics in macromolecular crystallography
McCoy AJ
Curr Opin Struct Biol. 2002 Oct;12(5):670-3. Review.
doi Digital Object Identifier
PHENIX: building new software for automated crystallographic structure determination
Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC.
Acta Crystallogr D Biol Crystallogr. 2002 Nov;58(Pt 11):1948-54. Epub 2002 Oct 21.
Acta Cryst D
Molecular architecture and functional model of the endocytic AP2 complex
Collins BM, McCoy AJ, Kent HM, Evans PR, Owen DJ.
Cell. 2002 May 17;109(4):523-35.
Cell (subscription required)

2001

No publications

2000

ScFv multimers of the anti-neuraminidase antibody NC10: shortening of the linker in single-chain Fv fragment assembled in V(L) to V(H) orientation drives the formation of dimers, trimers, tetramers and higher molecular mass multimers
Dolezal O, Pearce LA, Lawrence LJ, McCoy AJ, Hudson PJ, Kortt AA.
Protein Eng. 2000 Aug;13(8):565-74.
doi Digital Object Identifier
The conformational activation of antithrombin. A 2.85-A structure of a fluorescein derivative reveals an electrostatic link between the hinge and heparin binding regions.
Huntington JA*, McCoy A*, Belzar KJ, Pei XY, Gettins PG, Carrell RW.
*authors contributed equally
J Biol Chem. 2000 May 19;275(20):15377-83
doi Digital Object Identifier

1999

Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod
McCoy AJ, Fucini P, Noegel AA, Stewart M.
Nat Struct Biol. 1999 Sep;6(9):836-41.
Nature Structural Biology (subscription required)
scFv multimers of the anti-neuraminidase antibody NC10: length of the linker between VH and VL domains dictates precisely the transition between diabodies and triabodies
Atwell JL, Breheney KA, Lawrence LJ, McCoy AJ, Kortt AA, Hudson PJ.
Protein Eng. 1999 Jul;12(7):597-604.
doi Digital Object Identifier
Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import
Kent HM, Moore MS, Quimby BB, Baker AM, McCoy AJ, Murphy GA, Corbett AH, Stewart M.
J Mol Biol. 1999 Jun 11;289(3):565-77.
doi Digital Object Identifier

1998

The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2)
Stewart M, Kent HM, McCoy AJ.
J Mol Biol. 1998 Dec 18;284(5):1517-27.
doi Digital Object Identifier
Three-dimensional structures of single-chain Fv-neuraminidase complexes
Malby RL*, McCoy AJ*, Kortt AA, Hudson PJ, Colman PM.
*authors contributed equally
J Mol Biol. 1998 Jun 19;279(4):901-10.
doi Digital Object Identifier
Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran
Stewart M, Kent HM, McCoy AJ.
J Mol Biol. 1998 Apr 3;277(3):635-46.
doi Digital Object Identifier
Structural basis for amoeboid motility in nematode sperm
Bullock TL, McCoy AJ, Kent HM, Roberts TM, Stewart M.
Nat Struct Biol. 1998 Mar;5(3):184-9.
Nature Structural Biology (subscription required)

1997

Crystallization and preliminary X-Ray diffraction characterization of a dimerizing fragment of the rod domain of the Dictyostelium gelation factor (ABP-120)
Fucini P, McCoy AJ, Gomez-Ortiz M, Schleicher M, Noegel AA, Stewart M.
J Struct Biol. 1997 Nov;120(2):192-5
doi Digital Object Identifier
Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran
Clarkson WD, Corbett AH, Paschal BM, Kent HM, McCoy AJ, Gerace L, Silver PA, Stewart M.
J Mol Biol. 1997 Oct 10;272(5):716-30.
doi Digital Object Identifier
The 1.8 Å crystal structure of winged bean albumin 1, the major albumin from Psophocarpus tetragonolobus (L.) DC
McCoy AJ, Kortt AA.
J Mol Biol. 1997 Jun 27;269(5):881-91.
doi Digital Object Identifier
Electrostatic complementarity at protein/protein interfaces
McCoy AJ, Chandana Epa V, Colman PM.
J Mol Biol. 1997 May 2;268(2):570-84.
doi Digital Object Identifier
Single-chain Fv fragments of anti-neuraminidase antibody NC10 containing five- and ten-residue linkers form dimers and with zero-residue linker a trimer
Kortt AA, Lah M, Oddie GW, Gruen CL, Burns JE, Pearce LA, Atwell JL, McCoy AJ, Howlett GJ, Metzger DW, Webster RG, Hudson PJ.
Protein Eng. 1997 Apr;10(4):423-33.
doi Digital Object Identifier

1996

Protein Structure and Interaction
McCoy AJ
Thesis (Ph. D)
University of Melbourne Library (not available for loan)
Retrieved from "https://www.phaser.cimr.cam.ac.uk/index.php?title=Airlie_J._McCoy&oldid=2443"