Difference between revisions of "Course"

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The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of CIMR, University of Cambridge and the MRC-LMB.
 
The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of CIMR, University of Cambridge and the MRC-LMB.
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{| class="wikitable"
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|-
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! colspan="3" | Lecture Topics
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|-
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| colspan="3" | <br />Basic concepts and practical aspects
 +
|-
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| Overview of X-ray crystallography
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| Randy Read
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| 9 November
 +
|-
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| Crystallisation: theory                and practice
 +
| Airlie McCoy
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| 16 November
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|-
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| Basic diffraction                theory: waves, interference, reciprocal space
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| Randy Read
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| 23 November
 +
|-
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| X-ray data collection:                indexing, strategy, processing
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| Andrew Leslie
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| 30 November
 +
|-
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| The phase problem:                introduction to phasing methods
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| Randy Read
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| 7 December
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|-
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| Introduction                to fitting, refinement and validation
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| Randy Read
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| 14 December
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|-
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| colspan="3" | <br />Advanced topics
 +
|-
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| Advanced diffraction:                waves, interference and complex numbers
 +
| Randy Read
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| 18 January
 +
|-
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| Advanced diffraction:                atoms, crystals and reciprocal space
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| Randy Read
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| 25 January
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|-
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| X-ray sources: from generators to synchrotrons
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| Gwyndaf Evans
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| 8 February
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|-
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| Data collection, processing, complications
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| Andrew Leslie
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| 15 February
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|-
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| Fourier transforms: structure                factors, phases and electron density
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| Randy Read
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| 22 February
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|-
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| The convolution                theorem and its applications
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| Randy Read
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| 29 February
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|-
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| Symmetry in real and reciprocal space
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| Anne Bloomer
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| 7 March
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|-
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| The Patterson function and its implications
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| Phil Evans
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| 28 March
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|-
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| Structure factor                statistics: Wilson statistics, SIGMAA...
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| Randy Read
 +
| 4 April
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|-
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| Maximum likelihood:                theory, and application to structure refinement
 +
| Randy Read
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| 11 April
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|-
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| Molecular replacement
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| Randy Read
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| 18 April
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|-
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| Isomorphous replacement
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| Randy Read
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| 25 April
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|-
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| Experimental phasing                by maximum likelihood
 +
| Randy Read
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| not presented
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|-
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| Anomalous scattering and MAD
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| Gwyndaf Evans
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| 2 May
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|-
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| Density modification: theory                and practice
 +
| Randy Read
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| 9 May
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|-
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| Fitting, refinement                and validation
 +
| Phil Evans
 +
| 16 May
 +
|-
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| Analysing protein structures
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| Arthur Lesk
 +
| 23 May
 +
|}

Revision as of 10:51, 16 October 2023

The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of CIMR, University of Cambridge and the MRC-LMB.

Lecture Topics

Basic concepts and practical aspects
Overview of X-ray crystallography Randy Read 9 November
Crystallisation: theory and practice Airlie McCoy 16 November
Basic diffraction theory: waves, interference, reciprocal space Randy Read 23 November
X-ray data collection: indexing, strategy, processing Andrew Leslie 30 November
The phase problem: introduction to phasing methods Randy Read 7 December
Introduction to fitting, refinement and validation Randy Read 14 December

Advanced topics
Advanced diffraction: waves, interference and complex numbers Randy Read 18 January
Advanced diffraction: atoms, crystals and reciprocal space Randy Read 25 January
X-ray sources: from generators to synchrotrons Gwyndaf Evans 8 February
Data collection, processing, complications Andrew Leslie 15 February
Fourier transforms: structure factors, phases and electron density Randy Read 22 February
The convolution theorem and its applications Randy Read 29 February
Symmetry in real and reciprocal space Anne Bloomer 7 March
The Patterson function and its implications Phil Evans 28 March
Structure factor statistics: Wilson statistics, SIGMAA... Randy Read 4 April
Maximum likelihood: theory, and application to structure refinement Randy Read 11 April
Molecular replacement Randy Read 18 April
Isomorphous replacement Randy Read 25 April
Experimental phasing by maximum likelihood Randy Read not presented
Anomalous scattering and MAD Gwyndaf Evans 2 May
Density modification: theory and practice Randy Read 9 May
Fitting, refinement and validation Phil Evans 16 May
Analysing protein structures Arthur Lesk 23 May
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