Difference between revisions of "Course"
From Phaserwiki
| Line 15: | Line 15: | ||
| 16 November | | 16 November | ||
|- | |- | ||
| − | | [Basic diffraction theory: waves, interference, reciprocal space | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Basic_diffraction/Diffraction.html Basic diffraction theory: waves, interference, reciprocal space |
| Randy Read | | Randy Read | ||
| 23 November | | 23 November | ||
|- | |- | ||
| − | | X-ray data collection: | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Basic_collection/Datacol.html X-ray data collection: indexing, strategy, processing] |
| Andrew Leslie | | Andrew Leslie | ||
| 30 November | | 30 November | ||
|- | |- | ||
| − | | The phase problem: | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Basic_phasing/Phasing.html The phase problem: introduction to phasing methods] |
| Randy Read | | Randy Read | ||
| 7 December | | 7 December | ||
|- | |- | ||
| − | | Introduction | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Basic_phasing/Phasing.html Introduction to fitting, refinement and validation |
| Randy Read | | Randy Read | ||
| 14 December | | 14 December | ||
| Line 33: | Line 33: | ||
| colspan="3" | <br />Advanced topics | | colspan="3" | <br />Advanced topics | ||
|- | |- | ||
| − | | Advanced diffraction: | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Adv_diff1/Diffraction.html Advanced diffraction: waves, interference and complex numbers] |
| Randy Read | | Randy Read | ||
| 18 January | | 18 January | ||
|- | |- | ||
| − | | Advanced diffraction: | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Adv_diff1/Diffraction2.html Advanced diffraction:atoms, crystals and reciprocal space] |
| Randy Read | | Randy Read | ||
| 25 January | | 25 January | ||
| Line 49: | Line 49: | ||
| 15 February | | 15 February | ||
|- | |- | ||
| − | | Fourier transforms: structure | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Fourier/Fourier.html Fourier transforms: structure factors, phases and electron density] |
| Randy Read | | Randy Read | ||
| 22 February | | 22 February | ||
| − | |- | + | |-] |
| − | | The convolution | + | | [https://www-structmed.cimr.cam.ac.uk/Course/Convolution/convolution.html The convolution theorem and its applications] |
| Randy Read | | Randy Read | ||
| 29 February | | 29 February | ||
| Line 65: | Line 65: | ||
| 28 March | | 28 March | ||
|- | |- | ||
| − | | Structure factor | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Statistics/statistics.html Structure factor statistics: Wilson statistics, SIGMAA...] |
| Randy Read | | Randy Read | ||
| 4 April | | 4 April | ||
|- | |- | ||
| − | | Maximum likelihood: | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Likelihood/likelihood.html Maximum likelihood: theory, and application to structure refinement] |
| Randy Read | | Randy Read | ||
| 11 April | | 11 April | ||
|- | |- | ||
| − | | Molecular replacement | + | | [https://www.phaser.cimr.cam.ac.uk/Course/MolRep/molrep.html Molecular replacement] |
| Randy Read | | Randy Read | ||
| 18 April | | 18 April | ||
| Line 81: | Line 81: | ||
| 25 April | | 25 April | ||
|- | |- | ||
| − | | Experimental phasing | + | | [https://www.phaser.cimr.cam.ac.uk/Course/Adv_phasing/Expphasing.html Experimental phasing by maximum likelihood] |
| Randy Read | | Randy Read | ||
| not presented | | not presented | ||
| Line 89: | Line 89: | ||
| 2 May | | 2 May | ||
|- | |- | ||
| − | | Density modification: theory | + | | [https://www-structmed.cimr.cam.ac.uk/Course/DenMod/index.htm Density modification: theory and practice] |
| Randy Read | | Randy Read | ||
| 9 May | | 9 May | ||
|- | |- | ||
| − | | Fitting, refinement | + | | [https://www-structmed.cimr.cam.ac.uk/Course/Fitting/fittingtalk.html Fitting, refinement and validation] |
| Phil Evans | | Phil Evans | ||
| 16 May | | 16 May | ||
Revision as of 12:03, 16 October 2023
The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of CIMR, University of Cambridge and the MRC-LMB.
| Lecture Topics | ||
|---|---|---|
Basic concepts and practical aspects | ||
| Overview of X-ray crystallography | Randy Read | 9 November |
| Crystallisation: theory and practice | Airlie McCoy | 16 November |
| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_diffraction/Diffraction.html Basic diffraction theory: waves, interference, reciprocal space | Randy Read | 23 November |
| X-ray data collection: indexing, strategy, processing | Andrew Leslie | 30 November |
| The phase problem: introduction to phasing methods | Randy Read | 7 December |
| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_phasing/Phasing.html Introduction to fitting, refinement and validation | Randy Read | 14 December |
Advanced topics | ||
| Advanced diffraction: waves, interference and complex numbers | Randy Read | 18 January |
| Advanced diffraction:atoms, crystals and reciprocal space | Randy Read | 25 January |
| X-ray sources: from generators to synchrotrons | Gwyndaf Evans | 8 February |
| Data collection, processing, complications | Andrew Leslie | 15 February |
| Fourier transforms: structure factors, phases and electron density | Randy Read | 22 February |
| The convolution theorem and its applications | Randy Read | 29 February |
| Symmetry in real and reciprocal space | Anne Bloomer | 7 March |
| The Patterson function and its implications | Phil Evans | 28 March |
| Structure factor statistics: Wilson statistics, SIGMAA... | Randy Read | 4 April |
| Maximum likelihood: theory, and application to structure refinement | Randy Read | 11 April |
| Molecular replacement | Randy Read | 18 April |
| Isomorphous replacement | Randy Read | 25 April |
| Experimental phasing by maximum likelihood | Randy Read | not presented |
| Anomalous scattering and MAD | Gwyndaf Evans | 2 May |
| Density modification: theory and practice | Randy Read | 9 May |
| Fitting, refinement and validation | Phil Evans | 16 May |
| Analysing protein structures | Arthur Lesk | 23 May |
