Difference between revisions of "Course"
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− | The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of CIMR, University of Cambridge and the MRC-LMB. | + | The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of Cambridge Institute for Medical Research (CIMR), University of Cambridge and the Medical Research Council Laboratory of Molecular Biology, Cambridge (MRC-LMB). |
{| class="wikitable" | {| class="wikitable" | ||
|- | |- | ||
− | ! colspan="3" | Lecture Topics | + | ! colspan="3" | <b>Lecture Topics</b> |
|- | |- | ||
− | | colspan="3" | <br />Basic concepts and practical aspects | + | | colspan="3" | <br /><b>Basic concepts and practical aspects</b> |
|- | |- | ||
| [http://www.phaser.cimr.cam.ac.uk/Course/Overview/Overview.html Overview of X-ray crystallography] | | [http://www.phaser.cimr.cam.ac.uk/Course/Overview/Overview.html Overview of X-ray crystallography] | ||
| Randy Read | | Randy Read | ||
− | | 9 November | + | | 9 November 1999 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Crystals/intro.html Crystallisation: theory and practice] | | [https://www.phaser.cimr.cam.ac.uk/Course/Crystals/intro.html Crystallisation: theory and practice] | ||
| Airlie McCoy | | Airlie McCoy | ||
− | | 16 November | + | | 16 November 1999 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_diffraction/Diffraction.html Basic diffraction theory: waves, interference, reciprocal space] | | [https://www.phaser.cimr.cam.ac.uk/Course/Basic_diffraction/Diffraction.html Basic diffraction theory: waves, interference, reciprocal space] | ||
| Randy Read | | Randy Read | ||
− | | 23 November | + | | 23 November 1999 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_collection/Datacol.html X-ray data collection: indexing, strategy, processing] | | [https://www.phaser.cimr.cam.ac.uk/Course/Basic_collection/Datacol.html X-ray data collection: indexing, strategy, processing] | ||
| Andrew Leslie | | Andrew Leslie | ||
− | | 30 November | + | | 30 November 1999 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_phasing/Phasing.html The phase problem: introduction to phasing methods] | | [https://www.phaser.cimr.cam.ac.uk/Course/Basic_phasing/Phasing.html The phase problem: introduction to phasing methods] | ||
| Randy Read | | Randy Read | ||
− | | 7 December | + | | 7 December 1999 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_refinement/Refinement.html Introduction to fitting, refinement and validation] | | [https://www.phaser.cimr.cam.ac.uk/Course/Basic_refinement/Refinement.html Introduction to fitting, refinement and validation] | ||
| Randy Read | | Randy Read | ||
− | | 14 December | + | | 14 December 1999 |
|- | |- | ||
− | | colspan="3" | <br />Advanced topics | + | | colspan="3" | <br /><b>Advanced topics</b> |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Adv_diff1/Diffraction.html Advanced diffraction: waves, interference and complex numbers] | | [https://www.phaser.cimr.cam.ac.uk/Course/Adv_diff1/Diffraction.html Advanced diffraction: waves, interference and complex numbers] | ||
| Randy Read | | Randy Read | ||
− | | 18 January | + | | 18 January 2000 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Adv_diff2/Diffraction2.html Advanced diffraction:atoms, crystals and reciprocal space] | | [https://www.phaser.cimr.cam.ac.uk/Course/Adv_diff2/Diffraction2.html Advanced diffraction:atoms, crystals and reciprocal space] | ||
| Randy Read | | Randy Read | ||
− | | 25 January | + | | 25 January 2000 |
|- | |- | ||
| X-ray sources: from generators to synchrotrons | | X-ray sources: from generators to synchrotrons | ||
| Gwyndaf Evans | | Gwyndaf Evans | ||
− | | 8 February | + | | 8 February 2000 |
|- | |- | ||
| Data collection, processing, complications | | Data collection, processing, complications | ||
| Andrew Leslie | | Andrew Leslie | ||
− | | 15 February | + | | 15 February 2000 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Fourier/Fourier.html Fourier transforms: structure factors, phases and electron density] | | [https://www.phaser.cimr.cam.ac.uk/Course/Fourier/Fourier.html Fourier transforms: structure factors, phases and electron density] | ||
| Randy Read | | Randy Read | ||
− | | 22 February | + | | 22 February 2000 |
|-] | |-] | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Convolution/convolution.html The convolution theorem and its applications] | | [https://www.phaser.cimr.cam.ac.uk/Course/Convolution/convolution.html The convolution theorem and its applications] | ||
| Randy Read | | Randy Read | ||
− | | 29 February | + | | 29 February 2000 |
|- | |- | ||
| Symmetry in real and reciprocal space | | Symmetry in real and reciprocal space | ||
| Anne Bloomer | | Anne Bloomer | ||
− | | 7 March | + | | 7 March 2000 |
|- | |- | ||
| The Patterson function and its implications | | The Patterson function and its implications | ||
| Phil Evans | | Phil Evans | ||
− | | 28 March | + | | 28 March 2000 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Statistics/statistics.html Structure factor statistics: Wilson statistics, SIGMAA...] | | [https://www.phaser.cimr.cam.ac.uk/Course/Statistics/statistics.html Structure factor statistics: Wilson statistics, SIGMAA...] | ||
| Randy Read | | Randy Read | ||
− | | 4 April | + | | 4 April 2000 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Likelihood/likelihood.html Maximum likelihood: theory, and application to structure refinement] | | [https://www.phaser.cimr.cam.ac.uk/Course/Likelihood/likelihood.html Maximum likelihood: theory, and application to structure refinement] | ||
| Randy Read | | Randy Read | ||
− | | 11 April | + | | 11 April 2000 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/MolRep/molrep.html Molecular replacement] | | [https://www.phaser.cimr.cam.ac.uk/Course/MolRep/molrep.html Molecular replacement] | ||
| Randy Read | | Randy Read | ||
− | | 18 April | + | | 18 April 2000 |
|- | |- | ||
| Isomorphous replacement | | Isomorphous replacement | ||
| Randy Read | | Randy Read | ||
− | | 25 April | + | | 25 April 2000 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Adv_phasing/Expphasing.html Experimental phasing by maximum likelihood] | | [https://www.phaser.cimr.cam.ac.uk/Course/Adv_phasing/Expphasing.html Experimental phasing by maximum likelihood] | ||
| Randy Read | | Randy Read | ||
− | | not presented | + | | not presented |
|- | |- | ||
| Anomalous scattering and MAD | | Anomalous scattering and MAD | ||
| Gwyndaf Evans | | Gwyndaf Evans | ||
− | | 2 May | + | | 2 May 2000 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/DenMod/index.htm Density modification: theory and practice] | | [https://www.phaser.cimr.cam.ac.uk/Course/DenMod/index.htm Density modification: theory and practice] | ||
| Randy Read | | Randy Read | ||
− | | 9 May | + | | 9 May 2000 |
|- | |- | ||
| [https://www.phaser.cimr.cam.ac.uk/Course/Fitting/fittingtalk.html Fitting, refinement and validation] | | [https://www.phaser.cimr.cam.ac.uk/Course/Fitting/fittingtalk.html Fitting, refinement and validation] | ||
| Phil Evans | | Phil Evans | ||
− | | 16 May | + | | 16 May 2000 |
|- | |- | ||
| Analysing protein structures | | Analysing protein structures | ||
| Arthur Lesk | | Arthur Lesk | ||
− | | 23 May | + | | 23 May 2000 |
|} | |} |
Latest revision as of 13:00, 16 October 2023
The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of Cambridge Institute for Medical Research (CIMR), University of Cambridge and the Medical Research Council Laboratory of Molecular Biology, Cambridge (MRC-LMB).
Lecture Topics | ||
---|---|---|
Basic concepts and practical aspects | ||
Overview of X-ray crystallography | Randy Read | 9 November 1999 |
Crystallisation: theory and practice | Airlie McCoy | 16 November 1999 |
Basic diffraction theory: waves, interference, reciprocal space | Randy Read | 23 November 1999 |
X-ray data collection: indexing, strategy, processing | Andrew Leslie | 30 November 1999 |
The phase problem: introduction to phasing methods | Randy Read | 7 December 1999 |
Introduction to fitting, refinement and validation | Randy Read | 14 December 1999 |
Advanced topics | ||
Advanced diffraction: waves, interference and complex numbers | Randy Read | 18 January 2000 |
Advanced diffraction:atoms, crystals and reciprocal space | Randy Read | 25 January 2000 |
X-ray sources: from generators to synchrotrons | Gwyndaf Evans | 8 February 2000 |
Data collection, processing, complications | Andrew Leslie | 15 February 2000 |
Fourier transforms: structure factors, phases and electron density | Randy Read | 22 February 2000 |
The convolution theorem and its applications | Randy Read | 29 February 2000 |
Symmetry in real and reciprocal space | Anne Bloomer | 7 March 2000 |
The Patterson function and its implications | Phil Evans | 28 March 2000 |
Structure factor statistics: Wilson statistics, SIGMAA... | Randy Read | 4 April 2000 |
Maximum likelihood: theory, and application to structure refinement | Randy Read | 11 April 2000 |
Molecular replacement | Randy Read | 18 April 2000 |
Isomorphous replacement | Randy Read | 25 April 2000 |
Experimental phasing by maximum likelihood | Randy Read | not presented |
Anomalous scattering and MAD | Gwyndaf Evans | 2 May 2000 |
Density modification: theory and practice | Randy Read | 9 May 2000 |
Fitting, refinement and validation | Phil Evans | 16 May 2000 |
Analysing protein structures | Arthur Lesk | 23 May 2000 |