Difference between revisions of "Course"

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The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of CIMR, University of Cambridge and the MRC-LMB.
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The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of Cambridge Institute for Medical Research (CIMR), University of Cambridge and the Medical Research Council Laboratory of Molecular Biology, Cambridge (MRC-LMB).
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{| class="wikitable"
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|-
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! colspan="3" | <b>Lecture Topics</b>
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|-
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| colspan="3" | <br /><b>Basic concepts and practical aspects</b>
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|-
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| [http://www.phaser.cimr.cam.ac.uk/Course/Overview/Overview.html  Overview of X-ray crystallography]
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| Randy Read
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| 9 November 1999
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Crystals/intro.html Crystallisation: theory and practice]
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| Airlie McCoy
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| 16 November 1999
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_diffraction/Diffraction.html Basic diffraction theory: waves, interference, reciprocal space]
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| Randy Read
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| 23 November 1999
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_collection/Datacol.html X-ray data collection: indexing, strategy, processing]
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| Andrew Leslie
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| 30 November 1999
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_phasing/Phasing.html The phase problem: introduction to phasing methods]
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| Randy Read
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| 7 December 1999
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Basic_refinement/Refinement.html Introduction to fitting, refinement and validation]
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| Randy Read
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| 14 December 1999
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|-
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| colspan="3" | <br /><b>Advanced topics</b>
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Adv_diff1/Diffraction.html Advanced diffraction: waves, interference and complex numbers]
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| Randy Read
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| 18 January 2000
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Adv_diff2/Diffraction2.html Advanced diffraction:atoms, crystals and reciprocal space]
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| Randy Read
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| 25 January 2000
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|-
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| X-ray sources: from generators to synchrotrons
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| Gwyndaf Evans
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| 8 February 2000
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|-
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| Data collection, processing, complications
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| Andrew Leslie
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| 15 February 2000
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Fourier/Fourier.html Fourier transforms: structure factors, phases and electron density]
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| Randy Read
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| 22 February 2000
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|-]
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| [https://www.phaser.cimr.cam.ac.uk/Course/Convolution/convolution.html The convolution theorem and its applications]
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| Randy Read
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| 29 February 2000
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|-
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| Symmetry in real and reciprocal space
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| Anne Bloomer
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| 7 March 2000
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|-
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| The Patterson function and its implications
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| Phil Evans
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| 28 March 2000
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Statistics/statistics.html Structure factor statistics: Wilson statistics, SIGMAA...]
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| Randy Read
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| 4 April 2000
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Likelihood/likelihood.html Maximum likelihood: theory, and application to structure refinement]
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| Randy Read
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| 11 April 2000
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/MolRep/molrep.html Molecular replacement]
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| Randy Read
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| 18 April 2000
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|-
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| Isomorphous replacement
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| Randy Read
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| 25 April 2000
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Adv_phasing/Expphasing.html Experimental phasing by maximum likelihood]
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| Randy Read
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| not presented
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|-
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| Anomalous scattering and MAD
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| Gwyndaf Evans
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| 2 May 2000
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/DenMod/index.htm Density modification: theory and practice]
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| Randy Read
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| 9 May 2000
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|-
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| [https://www.phaser.cimr.cam.ac.uk/Course/Fitting/fittingtalk.html Fitting, refinement and validation]
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| Phil Evans
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| 16 May 2000
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|-
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| Analysing protein structures
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| Arthur Lesk
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| 23 May  2000
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|}

Latest revision as of 12:00, 16 October 2023

The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of Cambridge Institute for Medical Research (CIMR), University of Cambridge and the Medical Research Council Laboratory of Molecular Biology, Cambridge (MRC-LMB).

Lecture Topics

Basic concepts and practical aspects
Overview of X-ray crystallography Randy Read 9 November 1999
Crystallisation: theory and practice Airlie McCoy 16 November 1999
Basic diffraction theory: waves, interference, reciprocal space Randy Read 23 November 1999
X-ray data collection: indexing, strategy, processing Andrew Leslie 30 November 1999
The phase problem: introduction to phasing methods Randy Read 7 December 1999
Introduction to fitting, refinement and validation Randy Read 14 December 1999

Advanced topics
Advanced diffraction: waves, interference and complex numbers Randy Read 18 January 2000
Advanced diffraction:atoms, crystals and reciprocal space Randy Read 25 January 2000
X-ray sources: from generators to synchrotrons Gwyndaf Evans 8 February 2000
Data collection, processing, complications Andrew Leslie 15 February 2000
Fourier transforms: structure factors, phases and electron density Randy Read 22 February 2000
The convolution theorem and its applications Randy Read 29 February 2000
Symmetry in real and reciprocal space Anne Bloomer 7 March 2000
The Patterson function and its implications Phil Evans 28 March 2000
Structure factor statistics: Wilson statistics, SIGMAA... Randy Read 4 April 2000
Maximum likelihood: theory, and application to structure refinement Randy Read 11 April 2000
Molecular replacement Randy Read 18 April 2000
Isomorphous replacement Randy Read 25 April 2000
Experimental phasing by maximum likelihood Randy Read not presented
Anomalous scattering and MAD Gwyndaf Evans 2 May 2000
Density modification: theory and practice Randy Read 9 May 2000
Fitting, refinement and validation Phil Evans 16 May 2000
Analysing protein structures Arthur Lesk 23 May 2000
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