Course
From Phaserwiki
The Macromolecular Crystallography course was presented in the 1999-2000 academic year to staff and students of CIMR, University of Cambridge and the MRC-LMB.
Lecture Topics | ||
---|---|---|
Basic concepts and practical aspects | ||
Overview of X-ray crystallography | Randy Read | 9 November |
Crystallisation: theory and practice | Airlie McCoy | 16 November |
Basic diffraction theory: waves, interference, reciprocal space | Randy Read | 23 November |
X-ray data collection: indexing, strategy, processing | Andrew Leslie | 30 November |
The phase problem: introduction to phasing methods | Randy Read | 7 December |
[https://www.phaser.cimr.cam.ac.uk/Course/Basic_phasing/Phasing.html Introduction to fitting, refinement and validation | Randy Read | 14 December |
Advanced topics | ||
Advanced diffraction: waves, interference and complex numbers | Randy Read | 18 January |
Advanced diffraction:atoms, crystals and reciprocal space | Randy Read | 25 January |
X-ray sources: from generators to synchrotrons | Gwyndaf Evans | 8 February |
Data collection, processing, complications | Andrew Leslie | 15 February |
Fourier transforms: structure factors, phases and electron density | Randy Read | 22 February |
The convolution theorem and its applications | Randy Read | 29 February |
Symmetry in real and reciprocal space | Anne Bloomer | 7 March |
The Patterson function and its implications | Phil Evans | 28 March |
Structure factor statistics: Wilson statistics, SIGMAA... | Randy Read | 4 April |
Maximum likelihood: theory, and application to structure refinement | Randy Read | 11 April |
Molecular replacement | Randy Read | 18 April |
Isomorphous replacement | Randy Read | 25 April |
Experimental phasing by maximum likelihood | Randy Read | not presented |
Anomalous scattering and MAD | Gwyndaf Evans | 2 May |
Density modification: theory and practice | Randy Read | 9 May |
Fitting, refinement and validation | Phil Evans | 16 May |
Analysing protein structures | Arthur Lesk | 23 May |